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Articles (95)
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1

Thrombo-inflammation in acute ischaemic stroke — implications for treatment

Stoll, Guido, Nieswandt, Bernhard

Journal:

Nature Reviews Neurology (formerly Nature Clinical Practice Neurology)

Année:

2019

Langue:

english

Fichier:

PDF, 1.44 MB

english, 2019

2

Sugar rush bleeds the brain

Nieswandt, Bernhard, Stoll, Guido

Journal:

Nature Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 987 KB

english, 2011

3

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke

Schuhmann, Michael K, Kraft, Peter, Stoll, Guido, Lorenz, Kristina, Meuth, Sven G, Wiendl, Heinz, Nieswandt, Bernhard, Sparwasser, Tim, Beyersdorf, Niklas, Kerkau, Thomas, Kleinschnitz, Christoph

Journal:

Journal of Cerebral Blood Flow and Metabolism

Année:

2015

Langue:

english

Fichier:

PDF, 403 KB

english, 2015

4

How is the formation of microthrombi after traumatic brain injury linked to inflammation?

Albert-Weissenberger, Christiane, Hopp, Sarah, Nieswandt, Bernhard, Sirén, Anna-Leena, Kleinschnitz, Christoph, Stetter, Christian

Journal:

Journal of Neuroimmunology

Année:

2019

Langue:

english

Fichier:

PDF, 406 KB

english, 2019

5

Local leukocyte invasion during hyperacute human ischemic stroke

Kollikowski, Alexander M., Schuhmann, Michael K., Nieswandt, Bernhard, Müllges, Wolfgang, Stoll, Guido, Pham, Mirko

Journal:

Annals of Neurology

Année:

2020

Langue:

english

Fichier:

PDF, 1.56 MB

english, 2020

6

Flow cytometric detection of activated mouse integrin αIIbβ3 with a novel monoclonal antibody

Wolfgang Bergmeier, Valerie Schulte, Gero Brockhoff, Ulrich Bier, Hubert Zirngibl, Bernhard Nieswandt

Journal:

Cytometry Part A

Année:

2002

Langue:

english

Fichier:

PDF, 286 KB

english, 2002

7

Both FcγRIV and FcγRIII are essential receptors mediating type II and type III autoimmune responses via FcRγ-LAT-dependent generation of C5a

Shahzad N. Syed, Stephanie Konrad, Kristina Wiege, Bernhard Nieswandt, Falk Nimmerjahn, Reinhold E. Schmidt, J. Engelbert Gessner

Journal:

European Journal of Immunology

Année:

2009

Langue:

english

Fichier:

PDF, 591 KB

english, 2009

8

Platelet receptor signaling in thrombus formation

David Stegner, Bernhard Nieswandt

Journal:

Journal of Molecular Medicine

Année:

2011

Langue:

english

Fichier:

PDF, 443 KB

english, 2011

9

Blood coagulation factor XII—a neglected player in stroke pathophysiology

Mirko Pham, Guido Stoll, Bernhard Nieswandt, Martin Bendszus, Christoph Kleinschnitz

Journal:

Journal of Molecular Medicine

Année:

2012

Langue:

english

Fichier:

PDF, 301 KB

english, 2012

10

Store-operated Ca2+entry in platelets occurs independently of transient receptor potential (TRP) C1

David Varga-Szabo, Kalwant S. Authi, Attila Braun, Markus Bender, Archana Ambily, Sheila R. Hassock, Thomas Gudermann, Alexander Dietrich, Bernhard Nieswandt

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2008

Langue:

english

Fichier:

PDF, 477 KB

english, 2008

11

Rac1 is essential for phospholipase C-γ2 activation in platelets

Irina Pleines, Margitta Elvers, Amrei Strehl, Miroslava Pozgajova, David Varga-Szabo, Frauke May, Anna Chrostek-Grashoff, Cord Brakebusch, Bernhard Nieswandt

Journal:

Pflügers Archiv European Journal of Physiology

Année:

2009

Langue:

english

Fichier:

PDF, 576 KB

english, 2009

12

Kindlin-3 is essential for integrin activation and platelet aggregation

Moser, Markus, Nieswandt, Bernhard, Ussar, Siegfried, Pozgajova, Miroslava, Fässler, Reinhard

Journal:

Nature Medicine

Année:

2008

Langue:

english

Fichier:

PDF, 307 KB

english, 2008

13

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

Moers, Alexandra, Nieswandt, Bernhard, Massberg, Steffen, Wettschureck, Nina, Grüner, Sabine, Konrad, Ildiko, Schulte, Valerie, Aktas, Barsom, Gratacap, Marie-Pierre, Simon, Melvin I

Journal:

Nature Medicine

Année:

2003

Langue:

english

Fichier:

PDF, 1.07 MB

english, 2003

14

Diminished Lymphocyte Adhesion and Alleviation of Allergic Responses by Small-Molecule- or Antibody-Mediated Inhibition of L-Selectin Functions

Oostingh, Gertie J, Ludwig, Ralf J, Enders, Sven, Grüner, Sabine, Harms, Gesche, Boehncke, W Henning, Nieswandt, Bernhard, Tauber, Rudolf, Schön, Michael P

Journal:

The Journal of Investigative Dermatology

Année:

2006

Langue:

english

Fichier:

PDF, 188 KB

english, 2006

15

Facilitating roles of murine platelet glycoprotein Ib and αIIbβ3 in phosphatidylserine exposure during vWF–collagen-induced thrombus formation

Marijke J. E. Kuijpers, Valerie Schulte, Cécile Oury, Theo Lindhout, Jos Broers, Marc F. Hoylaerts, Bernhard Nieswandt, Johan W. M. Heemskerk

Journal:

The Journal of Physiology

Année:

2004

Langue:

english

Fichier:

PDF, 291 KB

english, 2004

16

Ischaemic stroke: a thrombo-inflammatory disease?

Bernhard Nieswandt, Christoph Kleinschnitz, Guido Stoll

Journal:

The Journal of Physiology

Année:

2011

Langue:

english

Fichier:

PDF, 467 KB

english, 2011

17

STIM and Orai in platelet function

David Varga-Szabo, Attila Braun, Bernhard Nieswandt

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2011

18

Absence of GPIbα is responsible for aberrant membrane development during megakaryocyte maturation: Ultrastructural study using a transgenic model

Christel Poujol, Jerry Ware, Bernhard Nieswandt, Alan T Nurden, Paquita Nurden

Journal:

Experimental Hematology

Année:

2002

Langue:

english

Fichier:

PDF, 1.38 MB

english, 2002

19

The intrinsic pathway of coagulation is essential for thrombus stability in mice

Thomas Renné, Bernhard Nieswandt, David Gailani

Journal:

Blood Cells, Molecules, and Diseases

Année:

2006

Langue:

english

Fichier:

PDF, 132 KB

english, 2006

20

Transdermal 17-β estradiol replacement therapy reduces megakaryocyte GPVI expression

Hongquan Geng, Hui Zhang, Wei Zhang, Bernhard Nieswandt, Paul F. Bray, Xinghong Leng

Journal:

Thrombosis Research

Année:

2008

Langue:

english

Fichier:

PDF, 319 KB

english, 2008

21

Impact of glycoprotein VI and platelet adhesion on atherosclerosis—A possible role of fibronectin

Andreas Bültmann, Zhongmin Li, Silvia Wagner, Mario Peluso, Tanja Schönberger, Carla Weis, Ildiko Konrad, Konstantinos Stellos, Steffen Massberg, Bernhard Nieswandt, Meinrad Gawaz, Martin Ungerer, Göt

Journal:

Journal of Molecular and Cellular Cardiology

Année:

2010

Langue:

english

Fichier:

PDF, 1.55 MB

english, 2010

22

The C-terminal peptide of thrombospondin-1 stimulates distinct signaling pathways but induces an activation-independent agglutination of platelets and other cells

Simone Voit, Michael Udelhoven, Gereon Lill, Barsom Aktas, Bernhard Nieswandt, Karsten Schrör, Artur-Aron Weber

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 363 KB

english, 2003

23

Platelet-Mediated Modulation of Adaptive Immunity: A Communication Link between Innate and Adaptive Immune Compartments

Bennett D Elzey, Jun Tian, Robert J Jensen, Axel K Swanson, Jason R Lees, Steven R Lentz, Colleen S Stein, Bernhard Nieswandt, Yiqiang Wang, Beverly L Davidson, Timothy L Ratliff

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 316 KB

english, 2003

24

Oxidative Stress and Compartment of Gene Expression Determine Proatherosclerotic Effects of Inducible Nitric Oxide Synthase

Padmapriya Ponnuswamy, Eva Ostermeier, Angelika Schröttle, Jiqiu Chen, Paul L. Huang, Georg Ertl, Bernhard Nieswandt, Peter J. Kuhlencordt

Journal:

The American Journal of Pathology

Année:

2009

Langue:

english

Fichier:

PDF, 570 KB

english, 2009

25

Platelet GPVI: a target for antithrombotic therapy?!

Sebastian Dütting, Markus Bender, Bernhard Nieswandt

Journal:

Trends in Pharmacological Sciences

Année:

2012

Langue:

english

Fichier:

PDF, 664 KB

english, 2012

26

A platelet-mediated system for shuttling blood-borne bacteria to CD8α+ dendritic cells depends on glycoprotein GPIb and complement C3

Verschoor, Admar, Neuenhahn, Michael, Navarini, Alexander A, Graef, Patricia, Plaumann, Ann, Seidlmeier, Amelie, Nieswandt, Bernhard, Massberg, Steffen, Zinkernagel, Rolf M, Hengartner, Hans, Busch, D

Journal:

Nature Immunology

Année:

2011

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2011

27

Impaired brain development and reduced cognitive function in phospholipase D-deficient mice

Burkhardt, Ute, Stegner, David, Hattingen, Elke, Beyer, Sandra, Nieswandt, Bernhard, Klein, Jochen

Journal:

Neuroscience Letters

Année:

2014

Langue:

english

Fichier:

PDF, 676 KB

english, 2014

28

p53 DNA Binding Cooperativity Is Essential for Apoptosis and Tumor Suppression In Vivo

Timofeev, Oleg, Schlereth, Katharina, Wanzel, Michael, Braun, Attila, Nieswandt, Bernhard, Pagenstecher, Axel, Rosenwald, Andreas, Elsässer, Hans-Peter, Stiewe, Thorsten

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 3.71 MB

english, 2013

29

Combating innate inflammation: a new paradigm for acute treatment of stroke?

Stoll, Guido, Kleinschnitz, Christoph, Nieswandt, Bernhard

Journal:

Annals of the New York Academy of Sciences

Année:

2010

Langue:

english

Fichier:

PDF, 111 KB

english, 2010

30

The Nbeal2 −/− mouse as a model for the gray platelet syndrome

Deppermann, Carsten, Nurden, Paquita, Nurden, Alan T, Nieswandt, Bernhard, Stegner, David

Journal:

Année:

2013

Langue:

english

Fichier:

PDF, 414 KB

english, 2013

31

Platelets promote coagulation factor XII-mediated proteolytic cascade systems in plasma

Johne, Julia, Blume, Constanze, Benz, Peter M., Pozgajová, Miroslava, Ullrich, Melanie, Schuh, Kai, Nieswandt, Bernhard, Walter, Ulrich, Renné, Thomas

Journal:

Biological Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 126 KB

english, 2006

32

Platelets are relevant mediators of renal injury induced by primary endothelial lesions

Schwarzenberger, Claudia, Sradnick, Jan, Lerea, Kenneth M., Goligorsky, Michael S., Nieswandt, Bernhard, Hugo, Christian P. M., Hohenstein, Bernd

Journal:

AJP: Renal Physiology

Année:

2015

Langue:

english

Fichier:

PDF, 675 KB

english, 2015

33

Cholesterol loss during glutamate-mediated excitotoxicity

Sodero, Alejandro O, Vriens, Joris, Ghosh, Debapriya, Stegner, David, Brachet, Anna, Pallotto, Marta, Sassoè-Pognetto, Marco, Brouwers, Jos F, Helms, J Bernd, Nieswandt, Bernhard, Voets, Thomas, Dotti

Journal:

The EMBO Journal

Année:

2012

Langue:

english

Fichier:

PDF, 791 KB

english, 2012

34

Abstracts of papers presented at the XIXth European Platelet Meeting, 14th–16th October 2004, Dorint Resort & Spa, Bad Brückenau, Germany

Walter, Ulrich, Nieswandt, Bernhard, Grüner, Sabine, Aktas, Barsom

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 204 KB

english, 2005

35

Blocking Von Willebrand Factor for Treatment of Cutaneous Inflammation

Hillgruber, Carina, Steingräber, Annika K., Pöppelmann, Birgit, Denis, Cécile V., Ware, Jerry, Vestweber, Dietmar, Nieswandt, Bernhard, Schneider, Stefan W, Goerge, Tobias

Journal:

The Journal of Investigative Dermatology

Année:

2014

Langue:

english

Fichier:

PDF, 11.19 MB

english, 2014

36

Inhibition of Platelet GPIbα and Promotion of Melanoma Metastasis

Erpenbeck, Luise, Nieswandt, Bernhard, Schön, Margarete, Pozgajova, Miroslava, Schön, Michael P

Journal:

The Journal of Investigative Dermatology

Année:

2010

Langue:

english

Fichier:

PDF, 5.35 MB

english, 2010

37

Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke

Kraft, Peter, Schuhmann, Michael K., Fluri, Felix, Lorenz, Kristina, Zernecke, Alma, Stoll, Guido, Nieswandt, Bernhard, Kleinschnitz, Christoph

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2015

38

Inhibition of Platelet GPVI Protects Against Myocardial Ischemia–Reperfusion InjurySignificance

Pachel, Christina, Mathes, Denise, Arias-Loza, Anahi-Paula, Heitzmann, Wolfram, Nordbeck, Peter, Deppermann, Carsten, Lorenz, Viola, Hofmann, Ulrich, Nieswandt, Bernhard, Frantz, Stefan

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Année:

2016

Langue:

english

Fichier:

PDF, 2.13 MB

english, 2016

39

The Novel Oral Syk Inhibitor, Bl1002494, Protects Mice From Arterial Thrombosis and Thromboinflammatory Brain Infarction

van Eeuwijk, Judith M.M., Stegner, David, Lamb, David J., Kraft, Peter, Beck, Sarah, Thielmann, Ina, Kiefer, Friedemann, Walzog, Barbara, Stoll, Guido, Nieswandt, Bernhard

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Année:

2016

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2016

40

Light Sheet Fluorescence Microscopy in Intact Bones Reveals Spatial Limitations for Megakaryocyte Migration in the Murine Bone Marrow

van Eeuwijk, Judith M., Stegner, David, Angay, Oğuzhan, Gorelashvili, Mari, Pinnecker, Jürgen, Schulze, Harald, Nieswandt, Bernhard, Heinze, Katrin G.

Journal:

Biophysical Journal

Année:

2016

Langue:

english

Fichier:

PDF, 43 KB

english, 2016

41

Model systems for platelet receptor shedding

Bender, Markus, Stegner, David, Nieswandt, Bernhard

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 666 KB

english, 2016

42

Orai1 controls C5a-induced neutrophil recruitment in inflammation

Sogkas, Georgios, Vögtle, Timo, Rau, Eduard, Gewecke, Britta, Stegner, David, Schmidt, Reinhold E., Nieswandt, Bernhard, Gessner, J. Engelbert

Journal:

European Journal of Immunology

Année:

2015

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2015

43

STIM1, STIM2, and Orai1 regulate store-operated calcium entry and purinergic activation of microglia

Michaelis, Marlen, Nieswandt, Bernhard, Stegner, David, Eilers, Jens, Kraft, Robert

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 851 KB

english, 2015

44

Attenuation of Transplant Arteriosclerosis With Clopidogrel Is Associated With a Reduction of Infiltrating Dendritic Cells and Macrophages in Murine Aortic Allografts

Abele, Silke, Spriewald, Bernd M., Ramsperger-Gleixner, Martina, Wollin, Martina, Hiemann, Nicola E., Nieswandt, Bernhard, Weyand, Michael, Ensminger, Stephan M.

Journal:

Transplantation Journal

Année:

2009

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2009

45

FXIIa inhibitor rHA-Infestin-4: Safe thromboprotection in experimental venous, arterial and foreign surface-induced thrombosis

May, Frauke, Krupka, Jennifer, Fries, Marion, Thielmann, Ina, Pragst, Ingo, Weimer, Thomas, Panousis, Con, Nieswandt, Bernhard, Stoll, Guido, Dickneite, Gerhard, Schulte, Stefan, Nolte, Marc W.

Journal:

British Journal of Haematology

Année:

2016

Langue:

english

Fichier:

PDF, 597 KB

english, 2016

46

Targeting coagulation factor XII as a novel therapeutic option in brain trauma

Hopp, Sarah, Albert-Weissenberger, Christiane, Mencl, Stine, Bieber, Michael, Schuhmann, Michael K., Stetter, Christian, Nieswandt, Bernhard, Schmidt, Peter M., Monoranu, Camelia-Maria, Alafuzoff, Iri

Journal:

Annals of Neurology

Année:

2016

Langue:

english

Fichier:

PDF, 696 KB

english, 2016

47

The expression of mouse CLEC-2 on leucocyte subsets varies according to their anatomical location and inflammatory state

Lowe, Kate L., Navarro-Núñez, Leyre, Bénézech, Cécile, Nayar, Saba, Kingston, Bethany L., Nieswandt, Bernhard, Barone, Francesca, Watson, Steve P., Buckley, Christopher D., Desanti, Guillaume E.

Journal:

European Journal of Immunology

Année:

2015

Langue:

english

Fichier:

PDF, 823 KB

english, 2015

48

Cooperative and alternate functions for STIM1 and STIM2 in macrophage activation and in the context of inflammation

Sogkas, Georgios, Stegner, David, Syed, Shahzad N., Vögtle, Timo, Rau, Eduard, Gewecke, Britta, Schmidt, Reinhold E., Nieswandt, Bernhard, Gessner, Johannes Engelbert

Journal:

Immunity, Inflammation and Disease

Année:

2015

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2015

49

Proplatelet formation is selectively inhibited by collagen type I via Syk-independent GPVI signaling

Semeniak, Daniela, Kulawig, Rebecca, Stegner, David, Meyer, Imke, Schwiebert, Silke, Bösing, Hendrik, Eckes, Beate, Nieswandt, Bernhard, Schulze, Harald

Journal:

Journal of Cell Science

Année:

2016

Langue:

english

Fichier:

PDF, 4.96 MB

english, 2016

50

Differential effects of reduced glycoprotein VI levels on activation of murine platelets by glycoprotein VI ligands

SNELL, Daniel C., SCHULTE, Valerie, JARVIS, Gavin E., ARASE, Kanako, SAKURAI, Daiju, SAITO, Takashi, WATSON, Steve P., NIESWANDT, Bernhard

Journal:

Biochemical Journal

Année:

2002

Langue:

english

Fichier:

PDF, 299 KB

english, 2002